Figure 1From: On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEFMultidomain fragments and mutants of PRG generated in this study and their functional characterization; (A) diagrammatic representation of the expression vector used for all constructs; (B) The constructs used in this study, the k cat values and fold-enhancement of nucleotide exchange compared to uncatalyzed RhoA.Back to article page