Figure 9

Structure-based phylogenetic tree of hot dog fold proteins. The corresponding quaternary association and the subfamily numbers (see Additional file 1 &2) are given next to the PDB code. *These two are the structures of the N- and the C-terminal domains of the double hot dog of mouse Acyl-CoA thioesterase 7, crystallized separately. The biologically relevant intact protein was shown to form Tr_dh type of oligomer in solution [13].