TY - JOUR AU - Fratev, Filip F. AU - Jónsdóttir, Svava Ósk PY - 2009 DA - 2009/07/22 TI - An in silico study of the molecular basis of B-RAF activation and conformational stability JO - BMC Structural Biology SP - 47 VL - 9 IS - 1 AB - B-RAF kinase plays an important role both in tumour induction and maintenance in several cancers and it is an attractive new drug target. However, the structural basis of the B-RAF activation is still not well understood. SN - 1472-6807 UR - https://doi.org/10.1186/1472-6807-9-47 DO - 10.1186/1472-6807-9-47 ID - Fratev2009 ER -