Figure 1

Overall structure of the 66.3 kDa protein from mouse. (a) The residues are rainbow-coloured according to their position in the polypeptide chain from the N-terminus (blue) to the C-terminus (orange) and represented in cartoon mode with smoothed loops. (b) In the topology diagram, light blue circles represent helices below or above the anti-parallel β-sheets, on either side of them, blue circles show helices which sandwich the sheets, and light blue stars display helical structures in loops above or below the sandwich between both β-sheets. N(A), C(A), N(B) and C(B) mark the N- and C-termini of the 28 kDa and 40 kDa fragment, respectively.