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Table 2 Statistical Significance of DaliLite Z score and Ω in identifying different SCOP structural levels for the DS362 dataset

From: Exploring protein structural dissimilarity to facilitate structure classification

SCOP Level

Mean

Mean Norm

t-test

F-test

Max

Min

 

Z

Ω

Z

Ω

p-value 95%

p-value 95%

Z

Ω

Z

Ω

Class

2.68

0.91

0.07

0.55

10-16

10-1

7.50

1.60

2.00

0.44

Fold

3.72

0.77

0.17

0.46

10-16

10-8

8.50

1.22

2.00

0.27

Super-family

3.63

0.72

0.16

0.42

10-16

10-1

0.23

6.90

1.06

2.00

Family

6.28

0.39

0.43

0.20

10-7

0.31

11.90

0.95

2.00

0.08

  1. The statistical significance of difference in the mean of the normalized coefficient of dissimilarity (Ω) and DaliLite Z score in terms of Student's two-sided t-test at 95% confidence interval. The small p-values from the t-test indicate a significant difference in the mean value of the two scores for the respective shared SCOP level. The p-values for the F-test reported at 95% confidence interval indicate that the two-sided t-test is valid based on the assumption of equality of the two sample variances. Mean Norm = normalised mean.