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Table 4 Statistical Significance of DaliLite Z score and Ω in identifying different SCOP structural levels for the DSF600 dataset

From: Exploring protein structural dissimilarity to facilitate structure classification

SCOP Level

Mean

Mean Norm

t-test

F-test

Max

Min

 

Z

Ω

Z

Ω

p-value 95%

p-value 95%

Z

Ω

Z

Ω

Class

2.96

1.11

0.12

0.64

10-16

10-16

9.80

1.65

2.00

0.16

Fold

5.01

1.03

0.39

0.30

10-10

10-5

9.60

1.57

2.00

0.80

Super-family

4.79

1.05

0.24

0.54

10-11

10-2

13.00

1.33

2.20

0.72

Family

13.10

0.40

0.40

0.30

10-16

10-1

29.60

1.32

2.00

0.00

  1. The statistical significance of difference in the mean of the normalised coefficient of dissimilarity (Ω) and DaliLite Z score in terms of Student's two-sided t-test at 95% confidence interval. The small p-values from the t-test indicate a significant difference in the mean value of the two scores for the respective shared SCOP level. The p-values for the F-test reported at 95% confidence interval indicate that the two-sided t-test is valid based on the assumption of equality of the two sample variances. Mean Norm = normalised mean.