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Table 4 Human cancer genes containing potential all-parallel G-quadruplexes.

From: Molecular models for intrastrand DNA G-quadruplexes

Gene symbol

Gene name

AKT1

v-akt murine thymoma viral oncogene homolog 1

ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

ATF1

activating transcription factor 1

BCL3

B-cell CLL/lymphoma 3

BRCA2

familial breast/ovarian cancer gene 2

CARD11

caspase recruitment domain family, member 11

CDH11

cadherin 11, type 2, OB-cadherin (osteoblast)

CLTCL1

clathrin, heavy polypeptide-like 1

ELN

elastin

EPS15

epidermal growth factor receptor pathway substrate 15 (AF1p)

ERCC2

excision repair cross-complementing rodent repair deficiency complementation group 2 (xeroderma pigmentosum D)

ETV6

ets variant gene 6 (TEL oncogene)

FGFR3

fibroblast growth factor receptor 3

FNBP1

formin binding protein 1 (FBP17)

FOXP1

forkhead box P1

FSTL3

follistatin-like 3 (secreted glycoprotein)

GATA1

GATA binding protein 1 (globin transcription factor 1)

HIP1

huntingtin interacting protein 1

HOXA11

homeo box A11

HOXA13

homeo box A13

HOXA9

homeo box A9

IGK@

immunoglobulin kappa locus

IRF4

interferon regulatory factor 4

JAZF1

juxtaposed with another zinc finger gene 1

LHFP

lipoma HMGIC fusion partner

MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 (AF17)

MSI2

musashi homolog 2 (Drosophila)

MSN

moesin

MUC1

mucin 1, transmembrane

MYCL1

v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)

MYCN

v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

MYC

v-myc myelocytomatosis viral oncogene homolog (avian)

PIM1

pim-1 oncogene

POU2AF1

POU domain, class 2, associating factor 1 (OBF1)

PTEN

phosphatase and tensin homolog gene

RANBP17

RAN binding protein 17

RAP1GDS1

RAP1, GTP-GDP dissociation stimulator 1

RET

ret proto-oncogene

SEPT6

septin 6

SFRS3

splicing factor, arginine/serine-rich 3

SS18L1

synovial sarcoma translocation gene on chromosome 18-like 1

TAF15

TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68 kDa

TCF12

transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)

TMPRSS2

transmembrane protease, serine 2

TRIM33

tripartite motif-containing 33 (PTC7, TIF1G)

TSHR

thyroid stimulating hormone receptor

ZNFN1A1

zinc finger protein, subfamily 1A, 1 (Ikaros)