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Table 2 The list of 34 possible input feature sets.

From: Machine learning integration for predicting the effect of single amino acid substitutions on protein stability

# Representation PAM CB BFA BFB
1 SO - - - -
2 SO + - - -
3 TO - - - -
4 TO + - - -
5 TO - + - -
6 TO - - + -
7 TO - - - +
8 TO + + - -
9 TO + - + -
10 TO + - - +
11 TO - + + -
12 TO - + - +
13 TO - - + +
14 TO + + + -
15 TO + + - +
16 TO + - + +
17 TO - + + +
18 TO + + + +
19 ST - - - -
20 ST + - - -
21 ST - + - -
22 ST - - + -
23 ST - - - +
24 ST + + - -
25 ST + - + -
26 ST + - - +
27 ST - + + -
28 ST - + - +
29 ST - - + +
30 ST + + + -
31 ST + + - +
32 ST + - + +
33 ST - + + +
34 ST + + + +
  1. The new features to each of the three representations (SO, TO or ST) are added one at a time and as combinations of two and more. The original features are already given in Table 1 and are not shown here.