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Table 2 The list of 34 possible input feature sets.

From: Machine learning integration for predicting the effect of single amino acid substitutions on protein stability

#

Representation

PAM

CB

BFA

BFB

1

SO

-

-

-

-

2

SO

+

-

-

-

3

TO

-

-

-

-

4

TO

+

-

-

-

5

TO

-

+

-

-

6

TO

-

-

+

-

7

TO

-

-

-

+

8

TO

+

+

-

-

9

TO

+

-

+

-

10

TO

+

-

-

+

11

TO

-

+

+

-

12

TO

-

+

-

+

13

TO

-

-

+

+

14

TO

+

+

+

-

15

TO

+

+

-

+

16

TO

+

-

+

+

17

TO

-

+

+

+

18

TO

+

+

+

+

19

ST

-

-

-

-

20

ST

+

-

-

-

21

ST

-

+

-

-

22

ST

-

-

+

-

23

ST

-

-

-

+

24

ST

+

+

-

-

25

ST

+

-

+

-

26

ST

+

-

-

+

27

ST

-

+

+

-

28

ST

-

+

-

+

29

ST

-

-

+

+

30

ST

+

+

+

-

31

ST

+

+

-

+

32

ST

+

-

+

+

33

ST

-

+

+

+

34

ST

+

+

+

+

  1. The new features to each of the three representations (SO, TO or ST) are added one at a time and as combinations of two and more. The original features are already given in Table 1 and are not shown here.