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Figure 6 | BMC Structural Biology

Figure 6

From: Structural insight into the recognition of amino-acylated initiator tRNA by eIF5B in the 80S initiation complex

Figure 6

Comparison of the interactions between eIF5B, EF-Tu and aIF2γ with tRNA. Despite the same polarity and similar interfaces for the interactions between the translational β barrel fold and the single-stranded 3′ CCA-end, the tRNAs adopt significantly different overall orientations relative to the protein in ribosome-bound eIF5B (red) or the ternary complexes of S. solfataricus aIF2 (cyan; PDB: 3V11) and T. aquaticus EF-Tu (yellow; PDB: 1TTT). ASL is anticodon stem loop.

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