Figure 1From: Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from Leishmania braziliensis Lb NDK structure. (A) Cartoon representation of LbNDK protomer, showing secondary structure elements labeled according to the nomenclature proposed by Morera et al. [17]. Colors are used to highlight important regions: Kpn loop (orange), Head (yellow), C-terminal extension (purple) and dimer/trimer interfaces (red). (B) Cartoon representation of LbNDK subunit, colored according to the B-factor values, from blue (lowest) to red (highest). (C) Electrostatic surface representation colored by charge from red (negative) to blue (positive) generated using the PyMOL Charge-smoothed potential approach. Inside the highly positive active site cleft, a phosphate ion (stick representation) is bounded to Lys11, Asn114 and the conserved residue His117.Back to article page