Structure and sequence comparisons between
NDK. (A) CLUSTALW alignment of the C-terminal sequence from LmNDK and LbNDK. The region not modelled in the LbNDK crystal structure (gray) contains only two amino acids residues (Ala146 and Cys147) that are not conserved in LmNDK (Val146 and Ser147). (B) Cartoon representation of LbNDK structure superimposed in the LmNDK structure highlighting the C-terminal extension partially unfolded in LbNDK (modelled up to residue 142 and colored in yellow) and fully folded in LmNDK (purple). In sticks (purple) are residues that form a hydrophobic cluster that stabilize the C-terminal extension of LmNDK and Ser147 that is substituted by a cysteine in LbNDK.