Figure 3From: Modeling of the OX1R–orexin-A complex suggests two alternative binding modesComparison of the homology models. Pink and cyan: OX1R homology models based on OX2R and NTSR1 respectively. Gray: OX2R crystal structure [PDB:4S0V]. (A) Conformation of ECL2. (B and C) Residues facing the receptor cavity from TMs 1, 5–7 and TMs 2–5 respectively.Back to article page