Modelwise depth and orientation of top-ranking docking poses. (A) OX2R-based model, (B) NTSR1-based model, (C) NTSR1_TM6-based model, (D) CXCR4-based model. Direction of His26 side chain plotted with arrows, as seen from the extracellular side. For vertical peptides the arrows touch the inner circle, for tilted peptides the arrows are shorter. Scatter plots show RDOCK score as a function of binding depth. Poses below the filter threshold are shown in red.