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Fig. 2 | BMC Structural Biology

Fig. 2

From: Variations in periplasmic loop interactions determine the pH-dependent activity of the hexameric urea transporter UreI from Helicobacter pylori: a molecular dynamics study

Fig. 2

The different orientations of the periplasmic loop. a UreI at pH 2.0 and a zoom to the trapped conformation, facing the adjacent chain against clockwise. b Conformation of UreI at pH 6.0 and enlargement of the conformation observed related to the movement of PL1 loop toward PL2 (c) Orientation of PL1 loop at pH 7.4. It is observed that the PL1 loop loses coherence within the system, showing no pattern in their orientation. At the right, the covariance values are annoted for each pair of conditions

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