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Fig. 4 | BMC Structural Biology

Fig. 4

From: Variations in periplasmic loop interactions determine the pH-dependent activity of the hexameric urea transporter UreI from Helicobacter pylori: a molecular dynamics study

Fig. 4

Distance variations between periplasmic loops. Average distances of the loops of each subunit of the full hpUreI system at each pH condition were calculated and box plotted. The values were represented as the distance between residues H70 and D130 from PL1 and PL2, respectively. As can be seen, de distance of periplasmic loop at pH 2.0 is greater than the distance observed at pH 6.0 and 7.4. Statistical significance were calculated using t-test, where the groups pH 2.0/pH 6.0 and pH 2.0/pH 7.4 show a p-value < 0.05 (p = 0.00027 and p = 0.00046, respectively)

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