Fig. 4
Effect of the PPI prediction accuracy on dimer ranking by eRankPPI. The BM1755C and BM58C datasets are divided into two subsets with respect to the accuracy of interface residue prediction (MCC ≥0.3 and MCC <0.3). The average hit count ± standard deviation is then calculated separately for each subset. An asterisk indicates that the ranking capability of eRankPPI for hetero-dimers is significantly affected by the accuracy of PPI residue prediction with a p-value of <0.05