Fig. 4

Structure of the cytoplasmic domain of EccD_1mt. a Domain organization of EccD₁. The predicted transmembrane helices 1–11 are indicated by shaded rectangles. The protein construct used for crystallization is shown as a horizontal line. b cyto-EccD_1mt monomer in cartoon representation colored in rainbow colors from N-terminus (blue) to C-terminus (red). The secondary structure elements are labeled. c cyto-EccD_1mt dimer in cartoon representation with acidic residues shown in stick representation (see Fig. 5). d MBP-cyto-EccD_1mt dimer in cartoon representation with MBP moieties colored in grey and cyto-EccD_1mt domains colored in blue and purple. e A close-up view of the MBP-cyto-EccD_1mt dimer. The orientation corresponds to panel c