| | |
Distances in crystallographic structures (Å)
|
Bond Restraints (Å)
|
|---|
|
Residue pair
|
Exper.b (Å)
|
Inactive (PDB id: 2RH1)
|
Active (PDB id: 3SN6)
|
rstr1
|
rstr2
|
rstr3
|
rstr4
|
rstr5
|
|---|
|
Ser203Oγa-Asp113Cγa
|
8.0–10.0
|
11.2
|
10.3
|
17
|
8
|
17
|
17
|
8
|
|
Ser204Oγ-Asp113Cγ
|
8.0–10.0
|
14.2
|
12.4
|
14
|
10
|
14
|
14
|
10
|
|
Ser207Oγ-Asp113Cγ
|
8.0–10.0
|
11.5
|
10.4
|
11.7
|
8
|
11.7
|
11.7
|
8
|
|
Ser207Cα-Asp113Cα
|
N/A
|
12.2
|
12.0
|
-
|
-
|
-
|
17
|
-
|
|
Asn293Cβ1-Asp113Cβ
|
8.0–10.0
|
13.6
|
14.0
|
14
|
15
|
14
|
14
|
8
|
|
Phe289Cβ-Asp113Cβ
|
8.0–8.4
|
11.7
|
12.3
|
13
|
12
|
13
|
13
|
8
|
|
Asn312 Cβ-Asp113Cβ
|
8.0–8.4
|
9.1
|
8.6
|
10
|
9
|
10
|
10
|
8
|
|
Phe289Cβ-Asn312Cβ
|
8.0–8.4
|
5.5
|
5.5
|
5.5
|
5.5
|
5.5
|
5.5
|
8
|
-
aγ Oxygen, and β and γ Carbon atoms of the side chains were taken into consideration
-
bThese are the distance ranges observed previously in various experimental studies [28–33]
