From: A lack of peptide binding and decreased thermostability suggests that the CASKIN2 scaffolding protein SH3 domain may be vestigial
SH3
Mutation(s)
Tm (°C)
WT
none
50
2x
K290Y, R319W
70
6x
K290Y, H296E, A300E, R319W, Y336L, I341F