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Table 3 Thermal denaturation midpoints of CASKIN2 SH3 domain mutants

From: A lack of peptide binding and decreased thermostability suggests that the CASKIN2 scaffolding protein SH3 domain may be vestigial

SH3

Mutation(s)

Tm (°C)

WT

none

50

2x

K290Y, R319W

70

6x

K290Y, H296E, A300E, R319W, Y336L, I341F

70