Fig. 1
Representation of the TCRpMHC complex (PDB-ID 2bnq). The MHC class I molecule is depicted in green (i.e., α1, α2, and α3 chains). The β-microglobulin is colored in cyan and the peptide bound to MHC in magenta. The two chains of TCR, α and β, are represented in blue and red colors, respectively. In the present application, the domains shown as transparent are removed from the structure, and only the two variable domains of TCR (i.e., Vα and Vβ), the α1 and α2 chains of MHC as well as the peptide are modeled. In addition, the two centers of rotations CoRβ and CoRμ, are respectively represented by an orange and a black colored ball