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Table 1 Ortho and foamy domain comparison Z-score statistics

From: A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication

a

ortho-N

 

foamy-N

foamy-C

Virus

Pool

a-value

Z-score

Pool

a-value

Z-score

BLV6

300

0.552

4.073

244

0.542

3.692

BLV

251

0.550

4.494

184

0.400

3.669

HIV6

312

0.551

3.781

220

0.405

3.579

HIV1

312

0.573

3.703

213

0.402

3.692

HML2

264

0.777

2.166

196

0.438

4.594

HTLV

400

0.592

4.030

328

0.457

4.013

JSRV

225

1.063

0.896

190

0.601

3.237

MLV

326

0.751

3.044

188

0.508

3.151

MPMV

269

0.565

3.902

185

0.523

2.918

PSIV

285

0.621

3.731

235

0.369

5.019

RELIK

234

0.639

3.688

237

0.700

3.297

RSV

204

0.543

3.123

239

0.526

3.542

b

ortho-C

BLV6

144

0.763

3.019

212

0.709

4.046

BLV

154

0.578

3.400

204

0.556

4.047

HIV1

157

0.593

3.760

174

0.705

3.362

HIV6

179

0.780

3.175

177

0.640

4.380

HML2

185

0.732

3.027

184

0.676

3.900

HTLV

156

0.685

3.847

163

0.694

2.807

RSV

155

0.448

3.754

235

0.403

5.009

  1. For each amino (N) and carboxy (C) domain pair between an ortho virus structure and the foamy virus capsid structure, a Z-score is calculated based on the a-value (Equ n. 1) derived from the comparison RMSD and length, relative to the pool of background decoy comparisons. The ortho virus identity is indicated by the code to the left, full details of which can be found in the “Methods” section. The top 12 Z-scores are high-lighted in bold, only three of which support a swapped domain match