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Table 1 Ortho and foamy domain comparison Z-score statistics

From: A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication

a ortho-N
  foamy-N foamy-C
Virus Pool a-value Z-score Pool a-value Z-score
BLV6 300 0.552 4.073 244 0.542 3.692
BLV 251 0.550 4.494 184 0.400 3.669
HIV6 312 0.551 3.781 220 0.405 3.579
HIV1 312 0.573 3.703 213 0.402 3.692
HML2 264 0.777 2.166 196 0.438 4.594
HTLV 400 0.592 4.030 328 0.457 4.013
JSRV 225 1.063 0.896 190 0.601 3.237
MLV 326 0.751 3.044 188 0.508 3.151
MPMV 269 0.565 3.902 185 0.523 2.918
PSIV 285 0.621 3.731 235 0.369 5.019
RELIK 234 0.639 3.688 237 0.700 3.297
RSV 204 0.543 3.123 239 0.526 3.542
b ortho-C
BLV6 144 0.763 3.019 212 0.709 4.046
BLV 154 0.578 3.400 204 0.556 4.047
HIV1 157 0.593 3.760 174 0.705 3.362
HIV6 179 0.780 3.175 177 0.640 4.380
HML2 185 0.732 3.027 184 0.676 3.900
HTLV 156 0.685 3.847 163 0.694 2.807
RSV 155 0.448 3.754 235 0.403 5.009
  1. For each amino (N) and carboxy (C) domain pair between an ortho virus structure and the foamy virus capsid structure, a Z-score is calculated based on the a-value (Equ n. 1) derived from the comparison RMSD and length, relative to the pool of background decoy comparisons. The ortho virus identity is indicated by the code to the left, full details of which can be found in the “Methods” section. The top 12 Z-scores are high-lighted in bold, only three of which support a swapped domain match