Fig. 6

Selectivity filter of the modelled human AQP8. a The monomeric model of HsAQP8 (slate blue) is aligned to the template AtTIP2;1 (rainbow). The residues in the selectivity filters are shown in stick representation. b Close up of the residues in the selectivity filters. Selectivity filter of HsAQP8 and AtTIP2;1 consists of H66 (H2^P), F139 (LC^P), I192 (H5^P), G201 (LE^P), R207 (HE^P) and H63 (H2^P), H131 (LC^P), I185 (H5^P), G194 (LE^P), R200 (HE^P), respectively. Oxygens of two water molecules in the selectivity filter are shown as red spheres