Skip to main content
Fig. 2 | BMC Structural Biology

Fig. 2

From: Three-dimensional models of Mycobacterium tuberculosis proteins Rv1555, Rv1554 and their docking analyses with sildenafil, tadalafil, vardenafil drugs, suggest interference with quinol binding likely to affect protein’s function

Fig. 2

Structural overlay of the M.tb monomer (Rv1555) and M.tb dimer (Rv1555, Rv1554) proteins complexed with sildenafil, tadalafil, vardenafil drugs on to the crystal structure of E. coli QFR tetrameric dimer protein complex (PDB code: 1L0V). The drug binding sites coincide with the equivalent menaquinol binding at the QD site for monomer and at the QP site for dimer M.tb proteins

Back to article page

BMC Structural Biology

ISSN: 1472-6807

Contact us