Fig. 8From: Three-dimensional models of Mycobacterium tuberculosis proteins Rv1555, Rv1554 and their docking analyses with sildenafil, tadalafil, vardenafil drugs, suggest interference with quinol binding likely to affect protein’s functionMultiple sequence alignment for the M.tb Rv1555 protein and its associated membrane subunit protein (Rv1554) in the dimer, along with their corresponding homologous sequences in the E.coli quinol-fumarate reductase membrane anchor subunit dimer protein (as in PDB code:1L0V). The residues are labelled sequentially for the individual subunits in the proteins. Residues involved in the drug-protein side-chain hydrogen bond interactions are indicated by arrowsBack to article page