Fig. 2

Distribution of confidence and coverage scores from T. pallidum proteome-wide structural modeling. Amino acid sequences of 978 protein-coding genes from T. pallidum subspecies pallidum were submitted to Phyre2 for structural modeling. a Pie chart indicating the distribution of the number of T. pallidum proteins with tertiary structure model predictions within five Phyre2 confidence score ranges. A confidence score of at least 90% was used for all subsequent analyses. b Pie chart indicating the distribution of the number of T. pallidum proteins modeled by Phyre2 with ≥90% confidence scores within 10% alignment coverage categories (0–100%). An alignment coverage of at least 10% was used for all subsequent analyses