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Fig. 5 | BMC Structural Biology

Fig. 5

From: Deciphering evolution of immune recognition in antibodies

Fig. 5

Conformational clusters of VH1–84 lineage. Sampled conformations were clustered (color coded) and represented in an RMSD versus time plot for respective free and bound (a) 5.11A1, (b) ED10 and (c) anti-uPAR antibodies, across 0.5 μs trajectory. Least RMSD representative antibody of each cluster is shown. Same color code between respective bound and free forms reflects the same cluster. Graphs in the lower panel show percent population of free and bound antibodies in each cluster

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