The 3rd Computational Structural Bioinformatics Workshop
Citation:
BMC Structural Biology
2010
10(Suppl 1):I1
Volume 10 Supplement 1
Selected articles from the Computational Structural Bioinformatics Workshop 2009
Research
Edited by Jing He and Di Wu
Computational Structural Bioinformatics Workshop 2009. Go to conference site.
Washington, DC, USA1 November 2009
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Tracing conformational changes in proteins
Many proteins undergo extensive conformational changes as part of their functionality. Tracing these changes is important for understanding the way these proteins function. Traditional biophysics-based conform...
Citation: BMC Structural Biology 2010 10(Suppl 1):S1 -
Prediction of protein long-range contacts using an ensemble of genetic algorithm classifiers with sequence profile centers
Prediction of long-range inter-residue contacts is an important topic in bioinformatics research. It is helpful for determining protein structures, understanding protein foldings, and therefore advancing the a...
Citation: BMC Structural Biology 2010 10(Suppl 1):S2 -
Generalized spring tensor models for protein fluctuation dynamics and conformation changes
In the last decade, various coarse-grained elastic network models have been developed to study the large-scale motions of proteins and protein complexes where computer simulations using detailed all-atom model...
Citation: BMC Structural Biology 2010 10(Suppl 1):S3 -
Structural interpretation of protein-protein interaction network
Currently a huge amount of protein-protein interaction data is available from high throughput experimental methods. In a large network of protein-protein interactions, groups of proteins can be identified as f...
Citation: BMC Structural Biology 2010 10(Suppl 1):S4 -
Discrimination of thermophilic and mesophilic proteins
There is a considerable literature on the source of the thermostability of proteins from thermophilic organisms. Understanding the mechanisms for this thermostability would provide insights into proteins gener...
Citation: BMC Structural Biology 2010 10(Suppl 1):S5 -
Mining for the antibody-antigen interacting associations that predict the B cell epitopes
Predicting B-cell epitopes is very important for designing vaccines and drugs to fight against the infectious agents. However, due to the high complexity of this problem, previous prediction methods that focus...
Citation: BMC Structural Biology 2010 10(Suppl 1):S6 -
Protein structure determination via an efficient geometric build-up algorithm
A protein structure can be determined by solving a so-called distance geometry problem whenever a set of inter-atomic distances is available and sufficient. However, the problem is intractable in general and h...
Citation: BMC Structural Biology 2010 10(Suppl 1):S7 -
Sequence periodicity in nucleosomal DNA and intrinsic curvature
Most eukaryotic DNA contained in the nucleus is packaged by wrapping DNA around histone octamers. Histones are ubiquitous and bind most regions of chromosomal DNA. In order to achieve smooth wrapping of the DN...
Citation: BMC Structural Biology 2010 10(Suppl 1):S8