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Page 9 of 12

  1. Fructans – β-D-fructofuranosyl polymers with a sucrose starter unit – constitute a carbohydrate reservoir synthesised by a considerable number of bacteria and plant species. Biosynthesis of levan (αGlc(1–2)βFr...

    Authors: Guoyu Meng and Klaus Fütterer

    Citation: BMC Structural Biology 2008 8:16

    Content type: Research article

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  2. A wide variety of stabilizing factors have been invoked so far to elucidate the structural basis of protein thermostability. These include, amongst the others, a higher number of ion-pairs interactions and hyd...

    Authors: Alessandro Paiardini, Riccardo Sali, Francesco Bossa and Stefano Pascarella

    Citation: BMC Structural Biology 2008 8:14

    Content type: Research article

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  3. PX domains have specialized protein structures involved in binding of phosphoinositides (PIs). Through binding to the various PIs PX domains provide site-specific membrane signals to modulate the intracellular...

    Authors: Gary N Parkinson, David Vines, Paul C Driscoll and Snezana Djordjevic

    Citation: BMC Structural Biology 2008 8:13

    Content type: Research article

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  4. The myelin sheath is a multilamellar membrane structure wrapped around the axon, enabling the saltatory conduction of nerve impulses in vertebrates. Myelin basic protein, one of the most abundant myelin-specif...

    Authors: Viivi Majava, Maxim V Petoukhov, Nobuhiro Hayashi, Päivi Pirilä, Dmitri I Svergun and Petri Kursula

    Citation: BMC Structural Biology 2008 8:10

    Content type: Research article

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  5. Thyroid receptors, TRα and TRβ, are involved in important physiological functions such as metabolism, cholesterol level and heart activities. Whereas metabolism increase and cholesterol level lowering could be...

    Authors: Lucas Bleicher, Ricardo Aparicio, Fabio M Nunes, Leandro Martinez, Sandra M Gomes Dias, Ana Carolina Migliorini Figueira, Maria Auxiliadora Morim Santos, Walter H Venturelli, Rosangela da Silva, Paulo Marcos Donate, Francisco AR Neves, Luiz A Simeoni, John D Baxter, Paul Webb, Munir S Skaf and Igor Polikarpov

    Citation: BMC Structural Biology 2008 8:8

    Content type: Research article

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  6. Although comparative modelling is routinely used to produce three-dimensional models of proteins, very few automated approaches are formulated in a way that allows inclusion of restraints derived from experime...

    Authors: Nicholas Furnham, Paul IW de Bakker, Swanand Gore, David F Burke and Tom L Blundell

    Citation: BMC Structural Biology 2008 8:7

    Content type: Research article

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  7. Purple acid phosphatases belong to the family of binuclear metallohydrolases and are involved in a multitude of biological functions, ranging from bacterial killing and bone metabolism in animals to phosphate ...

    Authors: Gerhard Schenk, Tristan W Elliott, Eleanor Leung, Lyle E Carrington, Nataša Mitić, Lawrence R Gahan and Luke W Guddat

    Citation: BMC Structural Biology 2008 8:6

    Content type: Research article

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  8. Eukaryotic translation elongation factor eEF1A directs the correct aminoacyl-tRNA to ribosomal A-site. In addition, eEF1A is involved in carcinogenesis and apoptosis and can interact with large number of non-t...

    Authors: Dmitry S Kanibolotsky, Oleksandra V Novosyl'na, Catherine M Abbott, Boris S Negrutskii and Anna V El'skaya

    Citation: BMC Structural Biology 2008 8:4

    Content type: Research article

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  9. The mechanism by which Hsp40 and other molecular chaperones recognize and interact with non-native polypeptides is a fundamental question. How Hsp40 co-operates with Hsp70 to facilitate protein folding is not ...

    Authors: Junbin Hu, Yunkun Wu, Jingzhi Li, Xinguo Qian, Zhengqing Fu and Bingdong Sha

    Citation: BMC Structural Biology 2008 8:3

    Content type: Research article

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  10. Comparative, or homology, modelling of protein structures is the most widely used prediction method when the target protein has homologues of known structure. Given that the quality of a model may vary greatly...

    Authors: David Piedra, Sergi Lois and Xavier de la Cruz

    Citation: BMC Structural Biology 2008 8:2

    Content type: Research article

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  11. Lipocalins are widely distributed in nature and are found in bacteria, plants, arthropoda and vertebra. In hematophagous arthropods, they are implicated in the successful accomplishment of the blood meal, inte...

    Authors: Benoit Adam, Benoit Charloteaux, Jerome Beaufays, Luc Vanhamme, Edmond Godfroid, Robert Brasseur and Laurence Lins

    Citation: BMC Structural Biology 2008 8:1

    Content type: Research article

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  12. Methionine aminopeptidase is a potential target of future antibacterial and anticancer drugs. Structural analysis of complexes of the enzyme with its inhibitors provides valuable information for structure-base...

    Authors: Ze-Qiang Ma, Sheng-Xue Xie, Qing-Qing Huang, Fa-Jun Nan, Thomas D Hurley and Qi-Zhuang Ye

    Citation: BMC Structural Biology 2007 7:84

    Content type: Research article

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  13. Insulin is a therapeutic protein that is widely used for the treatment of diabetes. Its biological function was discovered more than 80 years ago and it has since then been characterized extensively. Crystalli...

    Authors: Mathias Norrman and Gerd Schluckebier

    Citation: BMC Structural Biology 2007 7:83

    Content type: Research article

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  14. The snake venom group IIA secreted phospholipases A2 (SVPLA2), present in the Viperidae snake family exhibit a wide range of toxic and pharmacological effects. They exert their different functions by catalyzing t...

    Authors: Grazyna Faure, Veerabasappa T Gowda and Rachid C Maroun

    Citation: BMC Structural Biology 2007 7:82

    Content type: Research article

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  15. Chimeric hybrids derived from the rubredoxins of Pyrococcus furiosus (Pf) and Clostridium pasteurianum (Cp) provide a robust system for the characterization of protein conformational stability and dynamics in a d...

    Authors: David M LeMaster, Janet S Anderson, Limin Wang, Yi Guo, Hongmin Li and Griselda Hernández

    Citation: BMC Structural Biology 2007 7:81

    Content type: Research article

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  16. Pleckstrin homology (PH) domains are one of the most prevalent domains in the human proteome and represent the major phosphoinositide-binding module. These domains are often found in signaling proteins and fun...

    Authors: Sean G Jackson, Yi Zhang, Richard J Haslam and Murray S Junop

    Citation: BMC Structural Biology 2007 7:80

    Content type: Research article

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  17. Comparison of different protein x-ray structures has previously been made in a number of different ways; for example, by visual examination, by differences in the locations of secondary structures, by explicit...

    Authors: B David Silverman

    Citation: BMC Structural Biology 2007 7:77

    Content type: Research article

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  18. In conformational disorders, it is not evident which amyloid aggregates affect specific molecular mechanisms or cellular pathways, which cause disease because of their quantity and mechanical features and whic...

    Authors: Irantzu Pallarés, Clara Berenguer, Francesc X Avilés, Josep Vendrell and Salvador Ventura

    Citation: BMC Structural Biology 2007 7:75

    Content type: Research article

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  19. Structural studies of integral membrane proteins (IMPs) are hampered by inherent difficulties in their heterologous expression and in the purification of solubilized protein-detergent complexes (PDCs). The cho...

    Authors: Innokentiy Maslennikov, Georgia Kefala, Casey Johnson, Roland Riek, Senyon Choe and Witek Kwiatkowski

    Citation: BMC Structural Biology 2007 7:74

    Content type: Methodology article

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  20. Dimeric lectin-like oxidized low-density lipoprotein receptor-1 LOX-1 is the target receptor for oxidized low density lipoprotein in endothelial cells. In vivo assays revealed that in LOX-1 the basic spine argini...

    Authors: Mattia Falconi, Silvia Biocca, Giuseppe Novelli and Alessandro Desideri

    Citation: BMC Structural Biology 2007 7:73

    Content type: Research article

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  21. Ricin is a potent toxin and known bioterrorism threat with no available antidote. The ricin A-chain (RTA) acts enzymatically to cleave a specific adenine base from ribosomal RNA, thereby blocking translation. ...

    Authors: John H Carra, Colleen A McHugh, Sheila Mulligan, LeeAnn M Machiesky, Alexei S Soares and Charles B Millard

    Citation: BMC Structural Biology 2007 7:72

    Content type: Research article

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  22. Chitin self-assembly provides a dynamic extracellular biomineralization interface. The insoluble matrix of larval shells of the marine bivalve mollusc Mytilus galloprovincialis consists of chitinous material that...

    Authors: Veronika Schönitzer and Ingrid M Weiss

    Citation: BMC Structural Biology 2007 7:71

    Content type: Research article

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  23. Metabolic variations exist between the methionine salvage pathway of humans and a number of plants and microbial pathogens. 5-Methylthioribose (MTR) kinase is a key enzyme required for methionine salvage in pl...

    Authors: Shao-Yang Ku, Kenneth A Cornell and P Lynne Howell

    Citation: BMC Structural Biology 2007 7:70

    Content type: Research article

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  24. Ferredoxin-NADP(H) reductases (FNRs) are flavoenzymes that catalyze the electron transfer between NADP(H) and the proteins ferredoxin or flavodoxin. A number of structural features distinguish plant and bacter...

    Authors: Alessandro S Nascimento, Daniela L Catalano-Dupuy, Amanda Bernardes, Mario de Oliveira Neto, Maria Auxiliadora M Santos, Eduardo A Ceccarelli and Igor Polikarpov

    Citation: BMC Structural Biology 2007 7:69

    Content type: Research article

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  25. The prevalence of tuberculosis, the prolonged and expensive treatment that this disease requires and an increase in drug resistance indicate an urgent need for new treatments. The 1-deoxy-D-xylulose 5-phosphat...

    Authors: Lori Buetow, Amanda C Brown, Tanya Parish and William N Hunter

    Citation: BMC Structural Biology 2007 7:68

    Content type: Research article

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  26. In contrast to many other organisms, the malarial parasite Plasmodium falciparum possesses only one typical glutathione S-transferase. This enzyme, Pf GST, cannot be assigned to any of the known GST classes and r...

    Authors: Timir Tripathi, Stefan Rahlfs, Katja Becker and Vinod Bhakuni

    Citation: BMC Structural Biology 2007 7:67

    Content type: Research article

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  27. Differences in sweet taste perception among species depend on structural variations of the sweet taste receptor. The commercially used isovanillyl sweetener neohesperidin dihydrochalcone activates the human bu...

    Authors: Marcel Winnig, Bernd Bufe, Nicole A Kratochwil, Jay P Slack and Wolfgang Meyerhof

    Citation: BMC Structural Biology 2007 7:66

    Content type: Research article

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  28. The idea that the assembly of protein complexes is linked with protein disorder has been inferred from a few large complexes, such as the viral capsid or bacterial flagellar system, only. The relationship, whi...

    Authors: Hedi Hegyi, Eva Schad and Peter Tompa

    Citation: BMC Structural Biology 2007 7:65

    Content type: Research article

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  29. A right-handed, calcium-dependent β-roll structure found in secreted proteases and repeat-in-toxin proteins was used as a template for the design of minimal, soluble, monomeric polypeptides that would fold in ...

    Authors: Andrew J Scotter, Meng Guo, Melanie M Tomczak, Margaret E Daley, Robert L Campbell, Richard J Oko, David A Bateman, Avijit Chakrabartty, Brian D Sykes and Peter L Davies

    Citation: BMC Structural Biology 2007 7:63

    Content type: Research article

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  30. Pfam is a comprehensive collection of protein domains and families, with a range of well-established information including genome annotation. Pfam has two large series of functionally uncharacterized families,...

    Authors: Rajiv Tyagi, Stephen K Burley and Subramanyam Swaminathan

    Citation: BMC Structural Biology 2007 7:62

    Content type: Research article

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  31. Specific binding of proteins to DNA is one of the most common ways gene expression is controlled. Although general rules for the DNA-protein recognition can be derived, the ambiguous and complex nature of this...

    Authors: Elisabetta Moroni, Michele Caselle and Federico Fogolari

    Citation: BMC Structural Biology 2007 7:61

    Content type: Research article

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  32. Laccases belong to multicopper oxidases, a widespread class of enzymes implicated in many oxidative functions in pathogenesis, immunogenesis and morphogenesis of organisms and in the metabolic turnover of comp...

    Authors: Marta Ferraroni, Nina M Myasoedova, Vadim Schmatchenko, Alexey A Leontievsky, Ludmila A Golovleva, Andrea Scozzafava and Fabrizio Briganti

    Citation: BMC Structural Biology 2007 7:60

    Content type: Research article

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  33. Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (EC 2.4.2.8) is a central enzyme in the purine recycling pathway. Parasitic protozoa of the order Kinetoplastida cannot synthesize purines de novo and use th...

    Authors: Paulo S Monzani, Stefano Trapani, Otavio H Thiemann and Glaucius Oliva

    Citation: BMC Structural Biology 2007 7:59

    Content type: Research article

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  34. Human g rowth factor r eceptor b ound protein 7 (Grb7) is an adapter protein that mediates the coupling of tyrosine kinases with their downstream signaling pathways. Grb7 is frequently overexpressed in invasive a...

    Authors: Corrine J Porter, Jacqueline M Matthews, Joel P Mackay, Sharon E Pursglove, Jason W Schmidberger, Peter J Leedman, Stephanie C Pero, David N Krag, Matthew CJ Wilce and Jacqueline A Wilce

    Citation: BMC Structural Biology 2007 7:58

    Content type: Research article

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  35. Brd2 is a transcriptional regulator and belongs to BET family, a less characterized novel class of bromodomain-containing proteins. Brd2 contains two tandem bromodomains (BD1 and BD2, 46% sequence identity) in...

    Authors: Hongda Huang, Jiahai Zhang, Weiqun Shen, Xingsheng Wang, Jiawen Wu, Jihui Wu and Yunyu Shi

    Citation: BMC Structural Biology 2007 7:57

    Content type: Research article

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  36. The cell wall of Mycobacterium tuberculosis contains a wide range of phosphatidyl inositol-based glycolipids that play critical structural roles and, in part, govern pathogen-host interactions. Synthesis of phosp...

    Authors: Alistair K Brown, Guoyu Meng, Hemza Ghadbane, David J Scott, Lynn G Dover, Jérôme Nigou, Gurdyal S Besra and Klaus Fütterer

    Citation: BMC Structural Biology 2007 7:55

    Content type: Research article

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  37. Understanding and predicting protein stability upon point mutations has wide-spread importance in molecular biology. Several prediction models have been developed in the past with various algorithms. Statistic...

    Authors: Vijaya Parthiban, M Michael Gromiha, Madenhalli Abhinandan and Dietmar Schomburg

    Citation: BMC Structural Biology 2007 7:54

    Content type: Research article

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  38. One approach for speeding-up protein structure comparison is the projection approach, where a protein structure is mapped to a high-dimensional vector and structural similarity is approximated by distance between...

    Authors: Elena Zotenko, Rezarta Islamaj Dogan, W John Wilbur, Dianne P O'Leary and Teresa M Przytycka

    Citation: BMC Structural Biology 2007 7:53

    Content type: Research article

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  39. Lectins are mainly described as simple carbohydrate-binding proteins. Previous studies have tried to identify other binding sites, which possible recognize plant hormones, secondary metabolites, and isolated a...

    Authors: Plínio Delatorre, Bruno AM Rocha, Emmanuel P Souza, Taianá M Oliveira, Gustavo A Bezerra, Frederico BMB Moreno, Beatriz T Freitas, Tatiane Santi-Gadelha, Alexandre H Sampaio, Walter F Azevedo Jr and Benildo S Cavada

    Citation: BMC Structural Biology 2007 7:52

    Content type: Research article

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  40. The de novo design of peptides and proteins has recently surfaced as an approach for investigating protein structure and function. This approach vitally tests our knowledge of protein folding and function, while ...

    Authors: Rudresh Acharya, Madhvi Gupta, Suryanarayanarao Ramakumar, Udupi A Ramagopal and Virander S Chauhan

    Citation: BMC Structural Biology 2007 7:51

    Content type: Research article

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2017 Journal Metrics

  • Citation Impact
    1.308 - 2-year Impact Factor
    1.609 - 5-year Impact Factor
    0.643 - Source Normalized Impact per Paper (SNIP)
    1.024 - SCImago Journal Rank (SJR)

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    191,858 downloads


    Social Media Impact
    17 mentions

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