Figure 1

Crystal structures of the hypothetical protein PA0269 from (a) P. aeruginosa and (b) alkyl hydroperoxidase D (AhpD) from M. tuberculosis[2]. Although the proteins have similar function, the topologies of the proteins differ. Note the conserved helix motif (pink) has a different position in each structure. (c) Stereoview of the putative alkyl hydroperoxidase D from P. aeruginosa. The five side chains of the residues of the active site involved in the proton relay system are shown as black atoms.