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Table 2 Estimated kinetic constants for binding of HIV-1 Vpr75-90 to CypA by ITC

From: The Host-Pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains

Titration

n

Ka(×107 M-1)

KD(μM)

ΔH(kcal/mol)

-TΔS(kcal/mol)

1

0.98

0.9

0.12

-17.4

7.0

2

1.00

1.7

0.06

-16.5

7.5

Mean values ± S.E

 

1.3 ± 0.4

0.09 ± 0.03

-16.9 ± 0.5

7.3 ± 0.3

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BMC Structural Biology

ISSN: 1472-6807

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