Figure 3From: Functional region prediction with a set of appropriate homologous sequences-an index for sequence selection by integrating structure and sequence information with spatial statisticsFlow chart of our prediction method. The method consists of seven steps and is roughly classified into two parts, [A] Appropriate Sequence Selection for Functional Region Prediction (I-VI) and [B] Cluster Detection of Conserved Residues (VII). [I] Manipulation of sequences, [II] Manipulation of a structure, [III] MSA construction of the subset of retrieved sequences and calculation of conservation scores at all alignment sites, [IV] Integration of sequence and structure information, [V] Iteration process to find the maximum DSPAC, [VI] Selection of the appropriate set of homologous sequences with the maximum DSPAC, [VII] Cluster detection of conserved residues by using LMIC.Back to article page