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Table 1 IC 50 values of the inhibitor 2 compared with compound 1

From: Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking subsite C6

Inhibitor

NA

IC50 (μM)

1[17]

A/Udorn/72 NA (N2)

0.49

 

A/tern/Australia/G70c NA (N9)

4.4

 

B/Lee/40 NA

271

2[23]

H3N2

2

 

H1N1

20

 

A/tern/Australia/G70c NA (N9)

9.1 ± 2.2

 

B/Lee/40 NA

180