Figure 7

A structure-based multiple alignment of the sandwich-barrel hybrid motif (SBHM) domains from β and β' subunits of DDRPs and other proteins. The alignments were generated by structural superposition of representatives of the SBHM domains followed by addition of sequences neighbors of the representative structures. The conserved basic residue that forms a covalent linkage with the organic radical in biotin/lipoate-binding domain-type SBHM is shown in reverse shading. The individual sequence families of SBHMs are indicated to the right of the alignment. The waist-like loops are marked as 'L' in the secondary structure shown above the alignment. Species abbreviations are as in Fig. 1 and Fig. 2 Additional species abbreviations not given above are: Ana, Anabaena sp., Azvi, Azotobacter vinelandii, Bb, Borrelia burgdorferi, Brra, Brassica rapa, Ccr,Caulobacter crescentus, Cj, Campylobacter jejuni, Cpn, Chlamydophila pneumoniae, Haeso, Haemophilus somnus, Mge, Mycoplasma genitalium, Mj, Methanocaldococcus jannaschii, Nm, Neisseria meningitidis, Pab, Pyrococcus abyssi, PhLa, Phormidium laminosum, Pisa, Pisum sativum, Pmar, Prochlorococcus marinus, Prfr, Propionibacterium freudenreichii