Figure 6
From: A model of the ternary complex of interleukin-10 with its soluble receptors
Stereo diagram of each interface within a single IL-10/sIL-10R1/sIL-10R2 signaling unit (panel A). Polypeptide chains of IL-10 are shown in orange and cyan. sIL-10R1 is green and sIL-10R2 is magenta. Panels B, C and D represent close-up view of each interface, including contact residues. (B)- an interface between IL-10 and sIL-10R1, (C)- an interface between IL-10 and sIL-10R2, (D)- an interface between sIL-10R1 and sIL-10R2. Intermolecular hydrogen bonds calculated with in 3.2 Å distance cutoff are shown as blue dotted lines.