Figure 1

Energy relaxation. Each conformation in a decoy set (1r69) is relaxed from its starting conformation (top set) to the final conformation (bottom set), dashed lines correlate the starting and final conformations for a subset of the relaxation runs. The native conformation (red triangle) has the lowest energy and clustering of the fifty lowest energy decoys (blue triangles) predicts the native conformation. Inset: Energy relaxation leads to an enrichment of the near native decoys in the entire set of final conformations(blue set = 50 lowest energy decoys).