Figure 8

Searching for favourable interactions around phospho-acceptor sites in proteins that are not phosphorylated. Calculations were made with the non-phosphorylated set of proteins, from the phosphorylated/non-phosphorylated structure pairs, many of which undergo conformational change upon phosphorylation. A search was made, within a given radius, for the most positive potential peak around each site (real/phos or background/non-phos). Interaction energy is given for a single unit negative charge in the positive potential field. (a) Radius = 5 Å. (b) Radius = 10 Å. (c) Radius = 30 Å.