Table 2 Structural stability regions of Amylin
From: Computational re-engineering of Amylin sequence with reduced amyloidogenic potential
Structure | Sequence region |
|---|---|
characteristic | 1———–9———–18———–27———–37 |
Hydrophobic Core | —————LA-FLV——-FGAI————— |
Hydrophilic | -CNT-TC-TQ————————————- |
Surface | |
Beta Sheets | ——TCATQRLANFLVH——-AILSSTNVGSNT- |
Beta Turns | ————————–SSNNFG—————— |
Salt Bridges | —————————————————- |
Polar Regions | -CNT-TC-TQ—-N—-HSSNN——SSTN–SNTY |
Charged residues | K————-R———————————— |