Figure 2From: Human coronavirus OC43 3CL protease and the potential of ML188 as a broad-spectrum lead compound: Homology modelling and molecular dynamic studiesDOPE score profiles of template, 3D23, and homology model of OC43 3CLpro . General overlay of profiles indicates the generated model is close to its native structure. The spike at residue 50 corresponds to a variable loop structure for which OC43 3CLpro has assumed a more stable conformation.Back to article page