Fig. 3From: Computational analysis of the interactions of a novel cephalosporin derivative with β-lactamasesRepresentation of the interactions of 7-ACA derivative with the active sites of different β-lactamases. a) TEM-1; b) other class A β-lactamases; c) AmpC; d) Class D β-lactamases. The reactive Ser residue is indicated in bold, bound to one of the two possible reactive β-lactam rings (dotted line). The residues interacting more frequently with the groups discussed in the text (included in the circles) are shown in normal character, whereas less frequent interactions are shown in italics. In panel d, the residues belonging to OXA-10 are underlined. See text and Additional file 1: Table S1-S3 for further detailsBack to article page