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Featured article: A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication
Taylor, Stoye and Taylor applied protein structure comparison methods to resolve the ambiguous relationship between Spumaretrovirinae (foamy viruses) and the Orthoretrovirinae (e.g. HIV). Their results show the relationship conforms to a simple linear correspondence, with similarities suggesting the viral capsids originated from a common ancestor with a double domain structure.
The comparison methodology used in this article demonstrates an effective general approach to problems where the components have a high intrinsic level of similarity.
Classification of the human THAP protein family identifies an evolutionarily conserved coiled coil region
Aims and scope
- Alison Cuff, BioMed Central
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0.643 - Source Normalized Impact per Paper (SNIP)
1.024 - SCImago Journal Rank (SJR)
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