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BMC Structural Biology

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Featured article: A comparative analysis of the foamy and ortho virus capsid structures reveals an ancient domain duplication

Taylor, Stoye and Taylor applied protein structure comparison methods to resolve the ambiguous relationship between Spumaretrovirinae (foamy viruses) and the Orthoretrovirinae (e.g. HIV). Their results show the relationship conforms to a simple linear correspondence, with similarities suggesting the viral capsids originated from a common ancestor with a double domain structure.

The comparison methodology used in this article demonstrates an effective general approach to problems where the components have a high intrinsic level of similarity.

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Aims and scope

BMC Structural Biology is an open access, peer-reviewed journal that considers articles on investigations into the structure of biological macromolecules, including solving structures, structural and functional analyses, and computational modeling.

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2016 Journal Metrics

  • Citation Impact
    1.771 - 2-year Impact Factor
    1.696 - 5-year Impact Factor
    0.612 - Source Normalized Impact per Paper (SNIP)
    0.984 - SCImago Journal Rank (SJR)

    Usage 
    188,808 downloads
    1110 Usage Factor


    Social Media Impact
    22 mentions

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