Figure 2

Dynamically stable hydrogen bonds between protein and ligand. Dynamically stable hydrogen bonds (% of occurrence > 50) for LuxS+2SRH (a) Subunit A and (b) Subunit B and for LuxS+2KRI (c) Subunit A and (d) Subunit B between the protein and ligand. The hydrogen bonds are marked with brown dashed lines. The ligand is depicted in stick representation and the protein residues are represented as slate blue lines. The asymmetry in hydrogen bonding pattern in the two subunits of LuxS+2SRH and LuxS+2KRI around the ribosyl moiety of ligand (SRH/KRI) is highlighted with green rectangular boxes.