Figure 4

Example of a protein complex modeling. The images (a) -> (b) -> (c) -> (d) represent the modeled structures of the solutions given by DockAnalyse for the docking between proteins Isu1 and Isu2. The structures are displayed in the "surface" and "ribbon" formats and colored in green for protein Isu1 and yellow in the case of Isu2. The iron binding pocket of each of the proteins, which is composed of 3 cysteine residues, is displayed in a "ball and stick" format and colored in magenta. Isu1 and Isu2 iron binding pockets and interaction tails are labeled. The edges attempt to show the trajectory that may occur when these proteins interact to finally acquire the desired configuration required for ISC biogenesis.