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Table 2 MIPS functional classification and GO(Gene Ontology) assignments of biological processes and molecular functions for clusters 10, 14, and 15

From: Structural interpretation of protein-protein interaction network

Cluster # # proteins GO molecular function GO biological process MIPS functional classification
10 5 Cyclin-dependent protein kinase regulatory activity (5×10-5 ) Tubinding (4×10-3) Regulation of cyclin-dependent protein kinase activity (6×10 -5) Negative regulation of phosphate metabolic process (9×10-4) Enzymatic activity regulation / enzymeRegulator (5×10-4) Regulation of phosphate metabolism(9×10-3)
14 6 Recombinase activity ( 2×10-3) DNA strand annealing activity ( 3 ×10-3) Postreplication repair ( 1×10-4)regulation of cell cycle (5×10-4) Response to DNA damage stimulus (7 × 10-4) DNA repair (3×10-4) G2/M transition of mitotic cell cycle (7×10-4)
15 6 Protein serine/threonine/tyrosine kinase activity (5×10-3) Regulation of cell cycle (6×10-4)Negative regulation of meiotic cell cycle (10 ×10-4) Proteasomal degradation (ubiquitin/proteasomal pathway) (2×10-4 )