Table 2 MIPS functional classification and GO(Gene Ontology) assignments of biological processes and molecular functions for clusters 10, 14, and 15
From: Structural interpretation of protein-protein interaction network
Cluster # | # proteins | GO molecular function | GO biological process | MIPS functional classification |
|---|---|---|---|---|
10 | 5 | Cyclin-dependent protein kinase regulatory activity (5×10-5 ) Tubinding (4×10-3) | Regulation of cyclin-dependent protein kinase activity (6×10 -5) Negative regulation of phosphate metabolic process (9×10-4) | Enzymatic activity regulation / enzymeRegulator (5×10-4) Regulation of phosphate metabolism(9×10-3) |
14 | 6 | Recombinase activity ( 2×10-3) DNA strand annealing activity ( 3 ×10-3) | Postreplication repair ( 1×10-4)regulation of cell cycle (5×10-4) Response to DNA damage stimulus (7 × 10-4) | DNA repair (3×10-4) G2/M transition of mitotic cell cycle (7×10-4) |
15 | 6 | Protein serine/threonine/tyrosine kinase activity (5×10-3) | Regulation of cell cycle (6×10-4)Negative regulation of meiotic cell cycle (10 ×10-4) | Proteasomal degradation (ubiquitin/proteasomal pathway) (2×10-4 ) |