Figure 2

The structure of Sa MenH and position of the active site. The polypeptide is depicted as a ribbon with helices of the core domain colored red and b-strands blue, helices of the cap domain are copper colored. N and C mark the amino and carboxy termini of the protein. The catalytic triad consisting of Ser89, His243 and Asp216 are shown as sticks and mark the active site. Figures 2, 3, 4 and 6 prepared using PyMOL[41] and Illustrator (Adobe Systems Inc.).