Figure 2
The structure of the FS domain. (A) A stereo view of ribbon drawings of the FS domain. The two highly conserved sequences [17], PSPDW (mostly on the β5-β6 loop) and DAGTD (on the unusually long β7-β8 loop) are colored in red. Ca2+-binding residues on the top of the FS domain, the three disulfide bonds at the bottom of the domain and glycans are drawn in stick format. (B) The topology scheme of the FS domain. Figure 2, 3 and 5 were prepared using the program Pymol[37].