Figure 3
From: Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1
Comparison of matriptase:SFTI-1 and trypisn:SFTI-1 complexes. A) The matriptase Phe99 side chains (grey) and SFTI Phe12 -1 (cyan) undergo large rotation to widen the S2 subsite when compared to the structures of matriptase in benzamidine-bound form (light blue) and trypsin: SFTI-1 complex (deep blue). B) SFTI-1 Arg2 is accommodated at the S4 subsite (in surface representation and colored by electrostatic potential, ±7 kT/e).