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Figure 1 | BMC Structural Biology

Figure 1

From: Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin/mitomycin C resistance in other bacteria

Figure 1

Phenazine biosynthesis in Enterobacter agglomerans Eh1087. The phenazine biosynthesis operon of E. agglomerans Eh1087 contains 16 open reading frames, which are required to convert chorismic acid to phenazine-1,6-dicarboxylic acid (PDC; light grey) and further to D-alanyl griseoluteic acid (AGA; dark grey). EhpR (red) mediates resistance to self-produced AGA. It likely acts as a shuttle that delivers AGA to the major facilitator membrane transporter EhpJ (blue).

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BMC Structural Biology

ISSN: 1472-6807

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