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Table 1 SCOP folds included in the dataset of α-helices, β-strands and other conformation

From: Dependence of α-helical and β-sheet amino acid propensities on the overall protein fold type

SCOP Class

SCOP Fold

NE j 1

N j 2

α-helix

β-strand

Other

    

Nα j 3(fαexp j )6

Nβ j 4(fβexp j )7

NO j 5(fOexp j )8

All α proteins

4-helical cytokines

24

3,452

2,272

(50)

    
 

Alpha/alpha toroid

25

10,766

5,410

(32)

  

4,611

(56)

 

Alpha-alpha superhelix

48

11,524

8,213

(48)

  

3,270

(76)

 

Cytochrome P450

19

7,811

4,042

(43)

  

3,008

(63)

 

EF Hand-like

56

7,106

4,244

(54)

  

2,739

(76)

 

Ferritin-like

40

7,261

5,354

(35)

    
 

Four-helical up-and-down bundle

45

5,800

4,344

(55)

    
 

Globin-like

30

4,223

3,161

(56)

    
 

HD-domain/PDEase-like

12

3,487

2,248

(43)

    
 

Heme oxygenase-like

15

3,364

2,369

(43)

    
 

L-aspartase-like

14

6,699

4,154

(32)

  

2,217

(45)

 

Nuclear receptor ligand-binding domain

20

4,747

3,221

(48)

    

α/β

proteins

Adenine nucleotide alpha hydrolase-like

33

7,219

3,398

(49)

  

2,716

(60)

 

ALDH-like

11

5,122

2,198

(43)

    
 

Alpha/beta-Hydrolases

74

23,468

9,192

(42)

3,985

(23)

10,291

(54)

 

ClpP/crotonase

19

4,736

2,369

(38)

    
 

Flavodoxin-like

96

17,354

7,063

(49)

3,218

(24)

7,073

(58)

 

HAD-like

47

10,900

4,853

(54)

  

4,231

(59)

 

Isocitrate/Isopropylmalate dehydrogenase-like

17

6,267

2,869

(45)

  

2,239

(56)

 

NAD(P)-binding Rossmann-fold domains

100

26,500

12,116

(40)

4,312

(18)

10,072

(57)

 

Nucleotide-diphospho-sugar transferases

24

6,359

2,297

(47)

  

2,723

(61)

 

Periplasmic binding protein-like II

46

14,225

5,593

(49)

2,916

(29)

5,716

(59)

 

Phosphorylase/hydrolase-like

36

9,424

3,277

(43)

2,105

(22)

4,042

(57)

 

P-loop containing nucleoside triphosphate hydrolases

170

39,025

16,859

(52)

7,524

(27)

14,882

(64)

 

PLP-dependent transferases

77

30,112

13,025

(43)

4,509

(16)

12,578

(43)

 

Restriction endonuclease-like

30

6,407

2,631

(50)

  

2,447

(64)

 

Ribokinase-like

24

7,234

3,029

(42)

  

2,589

(59)

 

Ribonuclease H-like motif

33

6,808

2,832

(49)

  

2,585

(70)

 

S-adenosyl-L-methionine-dependent methyltransferases

92

23,315

8,567

(49)

5,538

(31)

9,210

(62)

 

SIS domain

14

4,150

2,171

(38)

    
 

Thioredoxin fold

82

11,085

3,845

(59)

2,400

(29)

4,840

(67)

 

TIM beta/alpha-barrel

261

81,525

35,904

(46)

12,411

(11)

33,210

(53)

 

Tryptophan synthase beta subunit-like PLP-dependent enzymes

18

6,296

2,821

(36)

  

2,503

(53)

 

UDP-Glycosyltransferase/glycogen phosphorylase

16

6,976

3,324

(44)

  

2,562

(56)

α + β

proteins

Acyl-CoA N-acyltransferases (Nat)

63

11,104

3,872

(57)

3,376

(33)

3,856

(74)

 

Cysteine proteinases

34

9,122

3,027

(44)

  

4,248

(64)

 

Ferredoxin-like

174

19,761

6,048

(57)

5,212

(36)

8,501

(73)

 

Protein kinase-like (PK-like)

57

16,585

6,566

(44)

2,783

(40)

7,236

(65)

 

Thioesterase/thiol ester dehydrase-isomerase

38

5,319

  

2,090

(43)

  
 

Zincin-like

33

9,786

4,555

(44)

  

4,099

(63)

All β proteins

6-bladed beta-propeller

18

6,195

  

2,785

(23)

3,083

(60)

 

Concanavalin A-like lectins/glucanases

60

13,290

  

6,242

(32)

6,122

(67)

 

Double-stranded beta-helix

68

15,315

  

5,425

(27)

7,075

(62)

 

Galactose-binding domain-like

29

4,522

  

2,191

(39)

2,077

(71)

 

Immunoglobulin-like beta-sandwich

117

13,954

  

6,176

(47)

7,225

(78)

 

Lipocalins

41

6,422

  

3,120

(45)

2,371

(75)

 

OB-fold

58

7,072

  

2,665

(41)

3,418

(75)

 

PH domain-like barrel

54

7,041

  

2,434

(42)

3,393

(83)

 

Single-stranded right-handed beta-helix

27

8,817

  

3,600

(31)

4,484

(59)

 

Trypsin-like serine proteases

41

9,275

  

3,290

(29)

4,827

(63)

  1. 1. NE j : The number of PDB entries in the fold, j.
  2. 2. N j : The number of residues in the fold, j.
  3. 3. N α j : The number of residues of α-helices in the fold, j.
  4. 4. N β j : The number of residues of β-strands in the fold, j.
  5. 5. N O j : The number of residues of other conformation in the fold, j.
  6. 6. f αexp j : Fraction (%) of exposed residues in α-helices in the fold, j.
  7. 7. f βexp j : Fraction (%) of exposed residues in β-strands in the fold, j.
  8. 8. f Oexp j : Fraction (%) of exposed residues in other conformation in the fold, j.