From: Dependence of α-helical and β-sheet amino acid propensities on the overall protein fold type
SCOP Class | SCOP Fold | NE j 1 | N j 2 | α-helix | β-strand | Other | |||
---|---|---|---|---|---|---|---|---|---|
Nα j 3(fαexp j )6 | Nβ j 4(fβexp j )7 | NO j 5(fOexp j )8 | |||||||
All α proteins | 4-helical cytokines | 24 | 3,452 | 2,272 | (50) | ||||
Alpha/alpha toroid | 25 | 10,766 | 5,410 | (32) | 4,611 | (56) | |||
Alpha-alpha superhelix | 48 | 11,524 | 8,213 | (48) | 3,270 | (76) | |||
Cytochrome P450 | 19 | 7,811 | 4,042 | (43) | 3,008 | (63) | |||
EF Hand-like | 56 | 7,106 | 4,244 | (54) | 2,739 | (76) | |||
Ferritin-like | 40 | 7,261 | 5,354 | (35) | |||||
Four-helical up-and-down bundle | 45 | 5,800 | 4,344 | (55) | |||||
Globin-like | 30 | 4,223 | 3,161 | (56) | |||||
HD-domain/PDEase-like | 12 | 3,487 | 2,248 | (43) | |||||
Heme oxygenase-like | 15 | 3,364 | 2,369 | (43) | |||||
L-aspartase-like | 14 | 6,699 | 4,154 | (32) | 2,217 | (45) | |||
Nuclear receptor ligand-binding domain | 20 | 4,747 | 3,221 | (48) | |||||
α/β proteins | Adenine nucleotide alpha hydrolase-like | 33 | 7,219 | 3,398 | (49) | 2,716 | (60) | ||
ALDH-like | 11 | 5,122 | 2,198 | (43) | |||||
Alpha/beta-Hydrolases | 74 | 23,468 | 9,192 | (42) | 3,985 | (23) | 10,291 | (54) | |
ClpP/crotonase | 19 | 4,736 | 2,369 | (38) | |||||
Flavodoxin-like | 96 | 17,354 | 7,063 | (49) | 3,218 | (24) | 7,073 | (58) | |
HAD-like | 47 | 10,900 | 4,853 | (54) | 4,231 | (59) | |||
Isocitrate/Isopropylmalate dehydrogenase-like | 17 | 6,267 | 2,869 | (45) | 2,239 | (56) | |||
NAD(P)-binding Rossmann-fold domains | 100 | 26,500 | 12,116 | (40) | 4,312 | (18) | 10,072 | (57) | |
Nucleotide-diphospho-sugar transferases | 24 | 6,359 | 2,297 | (47) | 2,723 | (61) | |||
Periplasmic binding protein-like II | 46 | 14,225 | 5,593 | (49) | 2,916 | (29) | 5,716 | (59) | |
Phosphorylase/hydrolase-like | 36 | 9,424 | 3,277 | (43) | 2,105 | (22) | 4,042 | (57) | |
P-loop containing nucleoside triphosphate hydrolases | 170 | 39,025 | 16,859 | (52) | 7,524 | (27) | 14,882 | (64) | |
PLP-dependent transferases | 77 | 30,112 | 13,025 | (43) | 4,509 | (16) | 12,578 | (43) | |
Restriction endonuclease-like | 30 | 6,407 | 2,631 | (50) | 2,447 | (64) | |||
Ribokinase-like | 24 | 7,234 | 3,029 | (42) | 2,589 | (59) | |||
Ribonuclease H-like motif | 33 | 6,808 | 2,832 | (49) | 2,585 | (70) | |||
S-adenosyl-L-methionine-dependent methyltransferases | 92 | 23,315 | 8,567 | (49) | 5,538 | (31) | 9,210 | (62) | |
SIS domain | 14 | 4,150 | 2,171 | (38) | |||||
Thioredoxin fold | 82 | 11,085 | 3,845 | (59) | 2,400 | (29) | 4,840 | (67) | |
TIM beta/alpha-barrel | 261 | 81,525 | 35,904 | (46) | 12,411 | (11) | 33,210 | (53) | |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | 18 | 6,296 | 2,821 | (36) | 2,503 | (53) | |||
UDP-Glycosyltransferase/glycogen phosphorylase | 16 | 6,976 | 3,324 | (44) | 2,562 | (56) | |||
α + β proteins | Acyl-CoA N-acyltransferases (Nat) | 63 | 11,104 | 3,872 | (57) | 3,376 | (33) | 3,856 | (74) |
Cysteine proteinases | 34 | 9,122 | 3,027 | (44) | 4,248 | (64) | |||
Ferredoxin-like | 174 | 19,761 | 6,048 | (57) | 5,212 | (36) | 8,501 | (73) | |
Protein kinase-like (PK-like) | 57 | 16,585 | 6,566 | (44) | 2,783 | (40) | 7,236 | (65) | |
Thioesterase/thiol ester dehydrase-isomerase | 38 | 5,319 | 2,090 | (43) | |||||
Zincin-like | 33 | 9,786 | 4,555 | (44) | 4,099 | (63) | |||
All β proteins | 6-bladed beta-propeller | 18 | 6,195 | 2,785 | (23) | 3,083 | (60) | ||
Concanavalin A-like lectins/glucanases | 60 | 13,290 | 6,242 | (32) | 6,122 | (67) | |||
Double-stranded beta-helix | 68 | 15,315 | 5,425 | (27) | 7,075 | (62) | |||
Galactose-binding domain-like | 29 | 4,522 | 2,191 | (39) | 2,077 | (71) | |||
Immunoglobulin-like beta-sandwich | 117 | 13,954 | 6,176 | (47) | 7,225 | (78) | |||
Lipocalins | 41 | 6,422 | 3,120 | (45) | 2,371 | (75) | |||
OB-fold | 58 | 7,072 | 2,665 | (41) | 3,418 | (75) | |||
PH domain-like barrel | 54 | 7,041 | 2,434 | (42) | 3,393 | (83) | |||
Single-stranded right-handed beta-helix | 27 | 8,817 | 3,600 | (31) | 4,484 | (59) | |||
Trypsin-like serine proteases | 41 | 9,275 | 3,290 | (29) | 4,827 | (63) |