Figure 6
Comparison of RES-ERα dimer characteristics. (A) Left and right figures represent RES-ERαagonist and ERαantagonist conformation of dimer, respectively. (B) Variations in Coulomb and LJ interaction energies between the two monomers of ERα bound with RES during the last 7 ns of simulation. Black and red colors represents Coulomb and LJ interaction between two monomer in agonist conformation, respectively, and gray and cyan colors represents Coulomb and LJ interaction between two monomers in antagonist conformation, respectively. (C) Variations in the number of hydrogen bonds between two monomers of ERα dimer bound with RES. Black and red line represents agonist and antagonist conformation of ERα, respectively.