Table 1 Average (μ) and standard deviations (σ) are reported for the lowest tree lRMSD over 10 executions of the method.
System | Start → Goal | μ ± σ over lowest lRMSDs (Å) | |||
|---|---|---|---|---|---|
| Â | Â | QUAD | LINEAR | UNIFORM | COMBINE 90-10 |
Trp-Cage (20 aa) | E → 1l2y (18 Å) | 1.91 ± 0.53 | 2.32 ± 0.78 | 2.34 ± 0.59 | 2.42 ± 0.43 |
|  | 1cfd → 1cll (10.7 Å) 1cll → 1cfd (10.7 Å) | 3.22 ± 0.13 3.42 ± 0.24 | 3.49 ± 0.42 3.66 ± 0.33 | 3.69 ± 0.26 3.97 ± 0.17 | 3.36 ± 0.13 3.49 ± 0.24 |
CaM (140 aa) | 1cfd → 2f3y (9.9 Å) 2f3y → 1cfd (9.9 Å) | 3.83 ± 0.43 3.50 ± 0.26 | 3.76 ± 0.52 3.54 ± 0.37 | 4.23 ± 0.31 3.80 ± 0.17 | 4.01 ± 0.34 3.57 ± 0.28 |
|  | 1cll → 2f3y (13.44 Å) 2f3y → 1cll (13.44 Å) | 1.76 ± 0.53 0.86 ± 0.25 | 1.52 ± 0.31 0.80 ± 0.20 | 1.44 ± 0.25 1.06 ± 0.31 | 1.50 ± 0.20 0.94 ± 0.14 |
AdK (214 aa) | 1ake → 4ake (6.95 Å) 4ake → 1ake (6.95 Å) | 4.20 ± 0.51 4.48 ± 0.86 | 4.39 ± 0.47 5.62 ± 0.80 | 5.47 ± 0.28 5.94 ± 0.15 | 4.32 ± 0.41 5.09 ± 0.69 |