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Table 1 Average (μ) and standard deviations (σ) are reported for the lowest tree lRMSD over 10 executions of the method.

From: Elucidating the ensemble of functionally-relevant transitions in protein systems with a robotics-inspired method

System Start Goal μ ± σ over lowest lRMSDs (Å)
   QUAD LINEAR UNIFORM COMBINE 90-10
Trp-Cage (20 aa) E 1l2y (18 Å) 1.91 ± 0.53 2.32 ± 0.78 2.34 ± 0.59 2.42 ± 0.43
  1cfd 1cll (10.7 Å)
1cll 1cfd (10.7 Å)
3.22 ± 0.13
3.42 ± 0.24
3.49 ± 0.42
3.66 ± 0.33
3.69 ± 0.26
3.97 ± 0.17
3.36 ± 0.13
3.49 ± 0.24
CaM (140 aa) 1cfd 2f3y (9.9 Å)
2f3y 1cfd (9.9 Å)
3.83 ± 0.43
3.50 ± 0.26
3.76 ± 0.52
3.54 ± 0.37
4.23 ± 0.31
3.80 ± 0.17
4.01 ± 0.34
3.57 ± 0.28
  1cll → 2f3y (13.44 Å)
2f3y → 1cll (13.44 Å)
1.76 ± 0.53
0.86 ± 0.25
1.52 ± 0.31
0.80 ± 0.20
1.44 ± 0.25
1.06 ± 0.31
1.50 ± 0.20
0.94 ± 0.14
AdK (214 aa) 1ake → 4ake (6.95 Å)
4ake → 1ake (6.95 Å)
4.20 ± 0.51
4.48 ± 0.86
4.39 ± 0.47
5.62 ± 0.80
5.47 ± 0.28
5.94 ± 0.15
4.32 ± 0.41
5.09 ± 0.69
  1. Weighting schemes for global bias over node selection are compared here. No local bias is used in the expansion procedure.